1999

D.J. Mooney and A.G. Mikos, “Growing New Organs,” Scientific American Presents, 10 (3), 10-15 (1999).

[Abstract Available on PubMed] [text]L. Lu, L. Kam, M. Hasenbein, K. Nyalakonda, R. Bizios, A. Göpferich, J.F. Young, and A.G. Mikos, “Retinal Pigment Epithelial Cell Function on Substrates with Chemically Micropatterned Surfaces,” Biomaterials, 20, 2351-2361 (1999).

[Abstract Available on PubMed] [PDF]W.T. Godbey, K.K. Wu, and A.G. Mikos, “Tracking the Intracellular Path of Poly(Ethylenimine)/DNA Complexes for Gene Delivery,” Proceed. Natl. Acad. Sci. USA, 96, 5177-5181 (1999).

[Abstract Available on PubMed] [text]D.J. Mooney and A.G. Mikos, “Growing New Organs,” Scientific American, 280 (4), 60-65 (1999).

[text]W.T. Godbey, K.K. Wu, and A.G. Mikos, “Poly(Ethylenimine) and Its Role in Gene Therapy,” J. Controlled Release, 60, 149-160 (1999).

[Abstract Available on PubMed] [PDF]W.T. Godbey, K.K. Wu, G.J. Hirasaki, and A.G. Mikos, “Improved Packing of Poly(Ethylenimine)/DNA Complexes Increases Transfection Efficiency,” Gene Therapy, 6, 1380-1388 (1999).

[Abstract Available on PubMed]A.S. Goldstein, G. Zhu, G.E. Morris, R.K. Meszlenyi, and A.G. Mikos, “Effect of Osteoblastic Culture Conditions on the Structure of Poly(DL-Lactic-co-Glycolic Acid) Foam Scaffolds,” Tissue Eng., 5, 421-433 (1999).

[Abstract Available on PubMed]D. Dean, N.S. Topham, C. Rimnac, A.G. Mikos, D.P. Goldberg, K. Jepsen, R. Redtfeldt, Q. Liu, D. Pennington, and R. Ratcheson, “Osseointegration of Preformed PMMA Craniofacial Prostheses Coated with Bone Marrow Impregnated Poly(DL-Lactic-co-Glycolic Acid) (PLGA) Foam,” Plast. Reconstr. Surg., 104, 705-712 (1999).

[Abstract Available on PubMed]E. Behravesh, P.S. Engel, A.W. Yasko, and A.G. Mikos, “Synthetic Biodegradable Polymers for Orthopaedic Applications,” Clin. Orthop. Rel. Res., 367S, S118-S125 (1999).

[Abstract Available on PubMed]R.C. Thomson, A.G. Mikos, E. Beahm, J.C. Lemon, W.C. Satterfield, T.B. Aufdemorte, and M.J. Miller, “Guided Tissue Fabrication from Periosteum Using Preformed Biodegradable Polymer Scaffolds,” Biomaterials, 20, 2007-2018 (1999).

[Abstract Available on PubMed] [PDF]A. Göpferich, S.J. Peter, A. Lucke, L. Lu, and A.G. Mikos, “Modulation of Marrow Stromal Cell Function Using Poly(D,L-Lactic Acid)-block-Poly(Ethylene Glycol)-Monomethyl Ether Surfaces,” J. Biomed. Mater. Res., 46, 390-398 (1999).

[Abstract Available on PubMed] [PDF]L. Lu, C.A. Garcia, and A.G. Mikos, “In Vitro Degradation of Thin Poly(DL-Lactic-co-Glycolic Acid) Films,” J. Biomed. Mater. Res., 46, 236-244 (1999).

[Abstract Available on PubMed] [PDF]G.R.D. Evans, K. Brandt, M.S. Widmer, L. Lu, R.K. Meszlenyi, P.K. Gupta, A.G. Mikos, J. Hodges, J. Williams, A. Gürlek, A. Nabawi, R. Lohman, and C.W. Patrick, Jr., “In Vivo Evaluation of Poly(L-Lactic Acid) Porous Conduits for Peripheral Nerve Regeneration,” Biomaterials, 20, 1109-1115 (1999).

[Abstract Available on PubMed] [PDF]L.J. Suggs and A.G. Mikos, “Development of Poly(Propylene Fumarate-co-Ethylene Glycol) as an Injectable Carrier for Endothelial Cells,” Cell Transplantation, 8, 345-350 (1999).

[Abstract Available on PubMed]L.J. Suggs, M.S. Shive, C.A. Garcia, J.M. Anderson, and A.G. Mikos, “In Vitro Cytotoxicity and In Vivo Biocompatibility of Poly(Propylene Fumarate-co-Ethylene Glycol) Hydrogels,” J. Biomed. Mater. Res., 46, 22-32 (1999).

[Abstract Available on PubMed] [PDF]W.T. Godbey, K.K. Wu, and A.G. Mikos, “Size Matters: Molecular Weight Affects the Efficiency of Poly(Ethylenimine) as a Gene Delivery Vehicle,” J. Biomed. Mater. Res., 45, 268-275 (1999).

[Abstract Available on PubMed] [PDF]L. Lu and A.G. Mikos, “Biodegradable Polymers for Cell Transplantation,” Science Medicine, 6 (1), 6-7 (1999).

S.J. Peter, L.J. Suggs, M.J. Yaszemski, P.S. Engel, and A.G. Mikos, “Synthesis of Poly(Propylene Fumarate) by Acylation of Propylene Glycol in the Presence of a Proton Scavenger,” J. Biomater. Sci., Polym. Ed., 10, 363-373 (1999).

[Abstract Available on PubMed]L.J. Suggs, J.L. West, and A.G. Mikos, “Platelet Adhesion on a Bioresorbable Poly(Propylene Fumarate-co-Ethylene Glycol) Copolymer,” Biomaterials, 20, 683-690 (1999).

[Abstract Available on PubMed] [PDF]S.J. Peter, P. Kim, A.W. Yasko, M.J. Yaszemski, and A.G. Mikos, “Crosslinking Characteristics of an Injectable Poly(Propylene Fumarate)/b-Tricalcium Phosphate Paste and Mechanical Properties of the Crosslinked Composite for Use as a Biodegradable Bone Cement,” J. Biomed. Mater. Res., 44, 314-321 (1999).

[Abstract Available on PubMed] [PDF]

1998

S.J. Peter, M.J. Miller, A.W. Yasko, M.J. Yaszemski, and A.G. Mikos, “Polymer Concepts in Tissue Engineering,” J. Biomed. Mater. Res. (Appl. Biomater.), 43, 422-427 (1998).

[Abstract Available on PubMed] [PDF]L.J. Suggs, R.S. Krishnan, C.A. Garcia, S.J. Peter, J.M. Anderson, and A.G. Mikos, “In Vitro and In Vivo Degradation of Poly(Propylene Fumarate-co-Ethylene Glycol) Hydrogels,” J. Biomed. Mater. Res., 42, 312-320 (1998).

[Abstract Available on PubMed] [PDF]L. Lu, C.A. Garcia, and A.G. Mikos, “Retinal Pigment Epithelium Cell Culture on Thin Biodegradable Poly(DL-Lactic-co-Glycolic Acid) Films,” J. Biomater. Sci., Polym. Ed., 11, 1187-1205 (1998).

[Abstract Available on PubMed]M.S. Widmer, P.K. Gupta, L. Lu, R.K. Meszlenyi, G.R.D. Evans, K. Brandt, T. Savel, A. Gurlek, C.W. Patrick, Jr., and A.G. Mikos, “Manufacture of Porous Biodegradable Polymer Conduits by an Extrusion Process for Guided Tissue Regeneration,” Biomaterials, 19, 1945-1955 (1998).

[Abstract Available on PubMed] [PDF]R.C. Thomson, M.J. Yaszemski, J.M. Powers, and A.G. Mikos, “Hydroxyapatite Fiber Reinforced Poly(a-Hydroxy Ester) Foams for Bone Regeneration,” Biomaterials, 19, 1935-1943 (1998).

[Abstract Available on PubMed] [PDF]J.E. Babensee, J.M. Anderson, L.V. McIntire, and A.G. Mikos, “Host Response to Tissue Engineered Devices,” Adv. Drug Deliv. Rev., 33, 111-139 (1998).

[Abstract Available on PubMed]S.L. Ishaug-Riley, G.M. Crane-Kruger, M.J. Yaszemski, and A.G. Mikos, “Three-Dimensional Culture of Rat Calvarial Osteoblasts in Porous Biodegradable Polymers,” Biomaterials, 19, 1405-1412 (1998).

[Abstract Available on PubMed] [PDF]S.J. Peter, C.R. Liang, D.J. Kim, M.S. Widmer, and A.G. Mikos, “Osteoblastic Phenotype of Rat Marrow Stromal Cells Cultured in the Presence of Dexamethasone, b-Glycerolphosphate, and L-Ascorbic Acid,” J. Cell. Biochem., 71, 55-62 (1998).

[Abstract Available on PubMed] [PDF]S.J. Peter, S.T. Miller, G. Zhu, A.W. Yasko, and A.G. Mikos, “In Vivo Degradation of a Poly(Propylene Fumarate)/b-Tricalcium Phosphate Injectable Composite Scaffold,” J. Biomed. Mater. Res., 41, 1-7 (1998).

[Abstract Available on PubMed] [PDF]L.J. Suggs, E.Y. Kao, L.L. Palombo, R.S. Krishnan, M.S. Widmer, and A.G. Mikos, “Preparation and Characterization of Poly(Propylene Fumarate-co-Ethylene Glycol) Hydrogels,” J. Biomater. Sci., Polym. Ed., 9, 653-666 (1998).

[Abstract Available on PubMed]M.C. Wake, P.D. Gerecht, L. Lu, and A.G. Mikos, “Effects of Biodegradable Polymer Particles on Rat Marrow-Derived Stromal Osteoblasts In Vitro,” Biomaterials, 19, 1255-1268 (1998).

[Abstract Available on PubMed] [PDF]

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1997

S.J. Peter, M.J. Yaszemski, L.J. Suggs, R.G. Payne, R. Langer, W.C. Hayes, M.R. Unroe, L.B. Alemany, P.S. Engel, and A.G. Mikos, “Characterization of Partially Saturated Poly(Propylene Fumarate) for Orthopaedic Application,” J. Biomater. Sci., Polym. Ed., 8, 893-904 (1997).

[Abstract Available on PubMed]R.L. Cleek, K.C. Ting, S.G. Eskin, and A.G. Mikos, “Microparticles of Poly(DL-Lactic-co-Glycolic Acid)/Poly(Ethylene Glycol) Blends for Controlled Drug Delivery,” J. Controlled Release, 48, 259-268 (1997).

[Abstract] [PDF]L.J. Suggs, R.G. Payne, M.J. Yaszemski, L.B. Alemany, and A.G. Mikos, “Synthesis and Characterization of a Block Copolymer Consisting of Poly(Propylene Fumarate) and Poly(Ethylene Glycol),” Macromolecules, 30, 4318-4323 (1997).

[HTML] [PDF]S.L. Ishaug, G.M. Crane, M.J. Miller, A.W. Yasko, M.J. Yaszemski, and A.G. Mikos, “Bone Formation by Three-Dimensional Stromal Osteoblast Culture in Biodegradable Polymer Scaffolds,” J. Biomed. Mater. Res., 36, 17-28 (1997).

[Abstract Available on PubMed] [PDF]S.L. Ishaug-Riley, G.M. Crane, A. Gurlek, M.J. Miller, M.J. Yaszemski, A.W. Yasko, and A.G. Mikos, “Ectopic Bone Formation by Marrow Stromal Osteoblast Transplantation Using Poly(DL-Lactic-co-Glycolic Acid) Foams Implanted into the Rat Mesentery,” J. Biomed. Mater. Res., 36, 1-8 (1997).

[Abstract Available on PubMed] [PDF]S.J. Peter, J.A. Nolley, M.S. Widmer, J.E. Merwin, M.J. Yaszemski, A.W. Yasko, P.S. Engel, and A.G. Mikos, “In Vitro Degradation of a Poly(Propylene Fumarate)/b-Tricalcium Phosphate Composite Orthopaedic Scaffold,” Tissue Eng., 3, 207-215 (1997).

R.L. Cleek, A.A. Rege, L.A. Denner, S.G. Eskin, and A.G. Mikos, “Inhibition of Smooth Muscle Cell Growth In Vitro by an Antisense Oligodeoxynucleotide Released from Poly(DL-Lactic-co-Glycolic Acid) Microparticles,” J. Biomed. Mater. Res., 35, 525-530 (1997).

[Abstract Available on PubMed] [PDF]L. Christenson, A.G. Mikos, D.F. Gibbons, and G.L. Picciolo, “Biomaterials for Tissue Engineering: Summary,” Tissue Eng., 3, 71-76 (1997).

K.B. Hellman, G.L. Picciolo, A.G. Mikos, and C.A. Vacanti, “Workshop on Tissue Engineering: Foreword,” Tissue Eng., 3, 65-66 (1997).

G.G. Giordano, R.C. Thomson, S.L. Ishaug, A.G. Mikos, S. Cumber, C.A. Garcia, and D. Lahiri-Munir, “Retinal Pigment Epithelium Cells Cultured on Synthetic Biodegradable Polymers,” J. Biomed. Mater. Res., 34, 87-93 (1997).

[Abstract Available on PubMed] [PDF]

1996

C.R. Ruder, P. Dixon, A.G. Mikos, and M.J. Yaszemski, “The Growth and Phenotypic Expression of Human Osteoblasts,” Cytotechnology, 22, 263-267 (1996).

L. Lu and A.G. Mikos, “The Importance of New Processing Techniques in Tissue Engineering,” MRS Bulletin, 21, 28-32 (1996).

M.J. Yaszemski, R.G. Payne, W.C. Hayes, R. Langer, and A.G. Mikos, “The In Vitro Degradation of a Poly(Propylene Fumarate)-Based Composite Material,” Biomaterials, 17, 2127-2130 (1996).

[Abstract Available on PubMed]M.C. Wake, P.K. Gupta, and A.G. Mikos, “Fabrication of Pliable Biodegradable Polymer Foams to Engineer Soft Tissues,” Cell Transplantation, 5, 465-473 (1996).

[Abstract Available on PubMed]S.L. Ishaug, R.G. Payne, M.J. Yaszemski, T.B. Aufdemorte, R. Bizios, and A.G. Mikos, “Osteoblast Migration on Poly(a-Hydroxy Esters),” Biotechnol. Bioeng., 50, 443-451 (1996).

A.C. Jen, M.C. Wake, and A.G. Mikos, “Hydrogels for Cell Immobilization,” Biotechnol. Bioeng., 50, 357-364 (1996).

M.J. Miller, D.P. Goldberg, A.W. Yasko, J.C. Lemon, W.C. Satterfield, M.C. Wake, and A.G. Mikos, “Guided Bone Growth in Sheep: A Model for Tissue-Engineered Bone Flaps,” Tissue Eng., 2, 51-59 (1996).

R.C. Thomson, G.G. Giordano, J.H. Collier, S.L. Ishaug, A.G. Mikos, D. Lahiri-Munir, and C.A. Garcia, “Manufacture and Characterization of Poly(a-Hydroxy Ester) Thin Films as Temporary Substrates for Retinal Pigment Epithelium Cells,” Biomaterials, 17, 321-327 (1996).

[Abstract Available on PubMed]M.J. Yaszemski, R.G. Payne, W.C. Hayes, R. Langer, and A.G. Mikos, “The Evolution of Bone Transplantation: Molecular, Cellular, and Tissue Strategies to Engineer Human Bone,” Biomaterials, 17, 175-185 (1996).

[Abstract Available on PubMed]

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1995

G.M. Crane, S.L. Ishaug, and A.G. Mikos, “Bone Tissue Engineering,” Nature Medicine, 1, 1322-1324 (1995).

A.D. Ouellette, K.K. Wu, and A.G. Mikos, “Cardiovascular Gene Transfer,” Tissue Eng., 1, 311-322 (1995).

R.C. Thomson, M.C. Wake, M.J. Yaszemski, and A.G. Mikos, “Biodegradable Polymer Scaffolds to Regenerate Organs,” Adv. Polym. Sci., 122, 245-274 (1995).

R.C. Thomson, M.J. Yaszemski, J.M. Powers, and A.G. Mikos, “Fabrication of Biodegradable Polymer Scaffolds to Engineer Trabecular Bone,” J. Biomater. Sci., Polym. Ed., 7, 23-38 (1995).

[Abstract Available on PubMed]M.C. Wake, A.G. Mikos, G. Sarakinos, J.P. Vacanti, and R. Langer, “Dynamics of Fibrovascular Tissue Growth in Hydrogel Foams,” Cell Transplantation, 4, 275-279 (1995).

[Abstract Available on PubMed]H.A. von Recum, R.L. Cleek, S.G. Eskin, and A.G. Mikos, “Degradation of Polydispersed Poly(L-Lactic Acid) to Modulate Lactic Acid Release,” Biomaterials, 16, 441-447 (1995).

[Abstract Available on PubMed]M.J. Yaszemski, R.G. Payne, W.C. Hayes, R. Langer, T.B. Aufdemorte, and A.G. Mikos, “The Ingrowth of New Bone Tissue and Initial Mechanical Properties of a Degrading Polymeric Composite Scaffold,” Tissue Eng., 1, 41-52 (1995).

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1994

S.L. Ishaug, M.J. Yaszemski, R. Bizios, and A.G. Mikos, “Osteoblast Function on Synthetic Biodegradable Polymers,” J. Biomed. Mater. Res., 28, 1445-1453 (1994).

[Abstract Available on PubMed]M.C. Wake, C.W. Patrick, Jr., and A.G. Mikos, “Pore Morphology Effects on the Fibrovascular Tissue Growth in Porous Polymer Substrates,” Cell Transplantation, 3, 339-341 (1994).

[Abstract Available on PubMed]A.G. Mikos, M.G. Papadaki, S. Kouvroukoglou, S.L. Ishaug, and R.C. Thomson, “Islet Transplantation to Create a Bioartificial Pancreas,” Biotechnol. Bioeng., 43, 673-677 (1994).

A.G. Mikos, A.J. Thorsen, L.A. Czerwonka, Y. Bao, R. Langer, D.N. Winslow, and J.P. Vacanti, “Preparation and Characterization of Poly(L-Lactic Acid) Foams,” Polymer, 35, 1068-1077 (1994).

A.G. Mikos, M.D. Lyman, L.E. Freed, and R. Langer, “Wetting of Poly(L-Lactic Acid) and Poly(DL-Lactic-co-Glycolic Acid) Foams for Tissue Culture,” Biomaterials, 15, 55-58 (1994).

[Abstract Available on PubMed]

1993

A.G. Mikos, G. Sarakinos, M.D. Lyman, D.E. Ingber, J.P. Vacanti, and R. Langer, “Prevascularization of Porous Biodegradable Polymers,” Biotechnol. Bioeng., 42, 716-723 (1993).

A.G. Mikos and N.A. Peppas, “Bioadhesive Phenomena in Controlled Release Systems,” Pharmakeftiki, 6, 1-10 (1993).

A.G. Mikos, G. Sarakinos, S.M. Leite, J.P. Vacanti, and R. Langer, “Laminated Three-Dimensional Biodegradable Foams for Use in Tissue Engineering,” Biomaterials, 14, 323-330 (1993).

[Abstract Available on PubMed]H.L. Wald, G. Sarakinos, M.D. Lyman, A.G. Mikos, J.P. Vacanti, and R. Langer, “Cell Seeding in Porous Transplantation Devices,” Biomaterials, 14, 270-278 (1993).

[Abstract Available on PubMed]A.G. Mikos, Y. Bao, L.G. Cima, D.E. Ingber, J.P. Vacanti, and R. Langer, “Preparation of Poly(Glycolic Acid) Bonded Fiber Structures for Cell Attachment and Transplantation,” J. Biomed. Mater. Res., 27, 183-189 (1993).

[Abstract Available on PubMed]L.E. Freed, J.C. Marquis, A. Nohria, J. Emmanual, A.G. Mikos, and R. Langer, “Neocartilage Formation In Vitro and In Vivo Using Cells Cultured on Synthetic Biodegradable Polymers,” J. Biomed. Mater. Res., 27, 11-23 (1993).

[Abstract Available on PubMed]

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1991

A.G. Mikos, E. Mathiowitz, R. Langer, and N.A. Peppas, “Interaction of Polymer Microspheres with Mucin Gels as a Means of Characterizing Polymer Retention on Mucus,” J. Colloid Interface Sci., 143, 366-373 (1991).

A.G. Mikos and C. Kiparissides, “Skin Formation in Heterogeneous Polymerization Reactions,” J. Membrane Sci., 59, 205-217 (1991).

A.G. Mikos and N.A. Peppas, “Brittle Fracture of Entangled Polymers,” J. Polym. Sci., Polym. Phys. Ed., 29, 837-841 (1991).

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1990

A.G. Mikos and N.A. Peppas, “Bioadhesive Analysis of Controlled-Release Systems. IV. An Experimental Method for Testing the Adhesion of Microparticles with Mucus,” J. Controlled Release, 12, 31-37 (1990).

A.B. Scranton, A.G. Mikos, L.C. Scranton, and N.A. Peppas, “The Physical Mechanism for the Production of Hydrophilic Polymer Microparticles from Aqueous Suspensions,” J. Appl. Polym. Sci., 40, 997-1004 (1990).

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1989

N.A. Peppas and A.G. Mikos, “Experimental Methods for Determination of Bioadhesive Bond Strength of Polymers with Mucus,” S.T.P. Pharma, 5, 187-191 (1989).

A.G. Mikos and N.A. Peppas, “Measurement of the Surface Tension of Mucin Solutions,” Int. J. Pharm., 53, 1-5 (1989).

A.G. Mikos and N.A. Peppas, “Brittle Fracture of Low Molecular Weight Polymers,” J. Mater. Sci., 24, 1612-1616 (1989).

A.G. Mikos and N.A. Peppas, “Polymer Chain Entanglements and Brittle Fracture. III. Critical Fracture Strength of Macromolecular Materials,” J. Mater. Sci. Lett., 8, 833-834 (1989).

A.G. Mikos and N.A. Peppas, “Polymer Chain Entanglements and Brittle Fracture. II. Autohesion of Linear Polymers,” Polymer, 30, 84-91 (1989).

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1988

A.G. Mikos and N.A. Peppas, “Polymer Chain Entanglements and Brittle Fracture,” J. Chem. Phys., 88, 1337-1342 (1988).

[PDF]A.G. Mikos and N.A. Peppas, “Healing and Fracture at the Interface between two Gels,” Europhys. Lett., 6, 403-406 (1988).

A.G. Mikos and N.A. Peppas, “Flory Interaction Parameter c for Hydrophilic Copolymers with Water,” Biomaterials, 9, 419-423 (1988).

[Abstract Available on PubMed]

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1987

A.G. Mikos and N.A. Peppas, “Prediction of Feed Comonomer and Solvent Composition for Monomer-Free Polymer Production,” Biomaterials, 8, 404-406 (1987).

[Abstract Available on PubMed]A.G. Mikos and N.A. Peppas, “A model for Prediction of the Structural Characteristics of EGDMA-Crosslinked PHEMA Microparticles Produced by Suspension Copolymerization/ Crosslinking,” J. Controlled Release, 5, 53-62 (1987).

A.G. Mikos, C.G. Takoudis, and N.A. Peppas, “Evidence of Unequal Vinyl Group Reactivity in Copolymerization/Crosslinking Reactions of Mono- and Divinyl Comonomers,” Polymer, 28, 998-1004 (1987).

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1986

N.A. Peppas, M.L. Brannon, R.S. Harland, J. Klier, S.R. Lustig, and A.G. Mikos, “Influence of the Polymer Structure on Controlled Solute Release,” Bull. Techn. Gattefossé, 79, 7-17 (1986).

A.G. Mikos and N.A. Peppas, “Systems for Controlled Release of Drugs. V. Bioadhesive Systems,” S.T.P. Pharma, 2, 705-716 (1986).

A.G. Mikos, C.G. Takoudis, and N.A. Peppas, “Reaction Engineering Aspects of Suspension Polymerization,” J. Appl. Polym. Sci., 31, 2647-2659 (1986).

A.G. Mikos, C.G. Takoudis, and N.A. Peppas, “Kinetic Modeling of Copolymerization/ Crosslinking Reactions,” Macromolecules, 19, 2174-2182 (1986).

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