Research Papers 2011-2020
2020
A. Conev, E.E. Litsa, M.R. Perez, M. Diba, A.G. Mikos, and L.E. Kavraki, “Machine Learning-Guided Three-Dimensional Printing of Tissue Engineering Scaffolds,” Tissue Eng. Part A, 26, 1359-1368 (2020).
M.L. Bedell, A.M. Navara, Y. Du, S. Zhang, and A.G. Mikos, “Polymeric Systems for Bioprinting,” Chem. Rev., 120, 10744-10792 (2020).
G.L. Koons, M. Diba, and A.G. Mikos, “Materials Design for Bone-Tissue Engineering,” Nature Rev. Mater., 5, 584-603 (2020).
E.‑C. Grosfeld, B.T. Smith, M. Santoro, I. Lodoso‑Torrecilla, J.A. Jansen, D.J.O. Ulrich, A.J. Melchiorri, D.W. Scott, A.G. Mikos, and J.J.J.P. van den Beucken, “Fast Dissolving Glucose Porogens for Early Calcium Phosphate Cement Degradation and Bone Regeneration,” Biomed. Mater., 15, 025002 (10pp) (2020).
2019
J. Lu, X. Yan, X. Sun, X. Shen, H. Yin, C. Wang, Y. Liu, C. Lu, H. Fu, S. Yang, Y. Wang, X. Sun, L. Zhao, S. Lu, A.G. Mikos, J. Peng, and X. Wang, “Synergistic Effects of Dual-Presenting VEGF- and BDNF-Mimetic Peptide Epitopes from Self-Assembling Peptide Hydrogels on Peripheral Nerve Regeneration,” Nanoscale, 11, 19943-19958 (2019).
G.L. Koons, K. Schenke-Layland, and A.G. Mikos, “Why, When, Who, What, How, and Where for Writing Literature Review Articles,” Ann. Biomed. Eng., 47, 2334-2340 (2019).
J. Navarro, J. Swayambunathan, M.E. Janes, M. Santoro, A.G. Mikos, and J.P. Fisher, “Dual-Chambered Membrane Bioreactor for Coculture of Stratified Cell Populations,” Biotechnol. Bioeng., 116, 3253-3268 (2019).
J.L. Guo, Y.S. Kim, and A.G. Mikos, “Biomacromolecules for Tissue Engineering: Emerging Biomimetic Strategies,” Biomacromolecules, 20, 2904-2912 (2019).
L. Diaz-Gomez, P.D. Kontoyiannis, A.J. Melchiorri, and A.G. Mikos, “Three-Dimensional Printing of Tissue Engineering Scaffolds with Horizontal Pore and Composition Gradients,” Tissue Eng. Part C: Methods, 25, 411-420 (2019).
A.M. Tatara, E. Watson, N.D. Albert, P.D. Kontoyiannis, D.P. Kontoyiannis, and A.G. Mikos, “A Murine Model of Cutaneous Aspergillosis for Evaluation of Biomaterials-based Local Delivery Therapies,” J. Biomed. Mater. Res. Part A, 107A, 1867-1874 (2019).
I. Lodoso-Torrecilla, E.C. Grosfeld, A. Marra, B.T. Smith, A.G. Mikos, D.J.O. Ulrich, J.A. Jansen, and J.J.J.P. van den Beucken, “Multimodal Porogen Platforms for Calcium Phosphate Cement Degradation,” J. Biomed. Mater. Res. Part A, 107A, 1713-1722 (2019).
J.L. Guo, Y.S. Kim, V.Y. Xie, B.T. Smith, E. Watson, J. Lam, H.A. Pearce, P.S. Engel, and A.G. Mikos, “Modular, Tissue-Specific, and Biodegradable Hydrogel Cross-Linkers for Tissue Engineering,” Science Adv., 5, eaaw7396 (11pp) (2019).
M.M. Smoak, A. Han, E. Watson, A. Kishan, K.J. Grande-Allen, E. Cosgriff-Hernandez, and A.G. Mikos, “Fabrication and Characterization of Electrospun Decellularized Muscle-Derived Scaffolds,” Tissue Eng. Part C: Methods, 25, 276-287 (2019).
S.M. Bittner, B.T. Smith, L. Diaz-Gomez, C.D. Hudgins, A.J. Melchiorri, D.W. Scott, J.P. Fisher, and A.G. Mikos, “Fabrication and Mechanical Characterization of 3D Printed Vertical Uniform and Gradient Scaffolds for Bone and Osteochondral Tissue Engineering,” Acta Biomaterialia, 90, 37-48 (2019).
A.M. Tatara, G.L. Koons, E. Watson, T.C. Piepergerdes, S.R. Shah, B.T. Smith, J. Shum, J.C. Melville, I.A. Hanna, N. Demian, T. Ho, A. Ratcliffe, J.J.J.P. van den Beucken, J.A. Jansen, M.E. Wong, and A.G. Mikos, “Biomaterials-Aided Mandibular Reconstruction Using In Vivo Bioreactors,” Proceed. Natl. Acad. Sci. USA, 116, 6954-6963 (2019).
M. Senturk, G. Lin, Z. Zuo, D. Mao, E. Watson, A.G. Mikos, and H.J. Bellen, “Ubiquilins Regulate Autophagic Flux through mTOR Signalling and Lysosomal Acidification,” Nature Cell Biol., 21, 384-396 (2019).
M.M. Smoak, H.A. Pearce, and A.G. Mikos, “Microfluidic Devices for Disease Modeling in Muscle Tissue,” Biomaterials, 198, 250-258 (2019).
Y.S. Kim, M.M. Smoak, A.J. Melchiorri, and A.G. Mikos, “An Overview of the Tissue Engineering Market in the United States from 2011 to 2018,” Tissue Eng. Part A, 25, 1-8 (2019).
L. Diaz-Gomez, B.T. Smith, P.D. Kontoyiannis, S.M. Bittner, A.J. Melchiorri, and A.G. Mikos, “Multimaterial Segmented Fiber Printing for Gradient Tissue Engineering,” Tissue Eng. Part C: Methods, 25, 12-24 (2019).
Y.S. Kim, M. Majid, A.J. Melchiorri, and A.G. Mikos, “Applications of Decellularized Extracellular Matrix in Bone and Cartilage Tissue Engineering,” Bioeng. Transl. Med., 4, 83-95 (2019).
G.L. Koons and A.G. Mikos, “Progress in Three-Dimensional Printing with Growth Factors,” J. Controlled Release, 295, 50-59 (2019).
2018
S.M. Bittner, J.L. Guo, and A.G. Mikos, “Spatiotemporal Control of Growth Factors in Three- Dimensional Printed Scaffolds,” Bioprinting, 11, e00032 (10pp) (2018).
A.M. Tatara, S. Wurster, C.R. Lockworth, N.D. Albert, T.J. Walsh, A.G. Mikos, G.T. Eisenhoffer, and D.P. Kontoyiannis, “Immunosuppressed Adult Zebrafish Model of Mucormycosis,” Antimicrob. Agents Chemother., 62, e00698-18 (2018).
E.J. Lee, T.M. Robinson, J.J. Tabor, A.G. Mikos, and J. Suh, “Reverse Transduction Can Improve Efficiency of AAV Vectors in Transduction-Resistant Cells,” Biotechnol. Bioeng., 115, 3042-3049 (2018).
S.M. Bittner, J.L. Guo, A. Melchiorri, and A.G. Mikos, “Three-Dimensional Printing of Multilayered Tissue Engineering Scaffolds,” Materials Today, 21, 861-874 (2018).
S. Wang, Z. Zhao, Y. Yang, A.G. Mikos, Z. Qiu, T. Song, F. Cui, X. Wang, and C. Zhang, “A High-Strength Mineralized Collagen Bone Scaffold for Large-Sized Cranial Bone Defect Repair in Sheep,” Regener. Biomater., 5, 283-292 (2018).
M. Whitely, S. Cereceres, P. Dhavalikar, K. Salhadar, T. Wilems, B. Smith, A.G. Mikos, and E. Cosgriff-Hernandez, “Improved In Situ Seeding of 3D Printed Scaffolds Using Cell-Releasing Hydrogels,” Biomaterials, 185, 194-204 (2018).
J. Lu, X. Shen, X. Sun, H. Yin, S. Yang, C. Lu, Y. Wang, Y. Liu, Y. Huang, Z. Yang, X. Dong, C. Wang, Q. Guo, L. Zhao, X. Sun, S. Lu, A.G. Mikos, J. Peng, and X. Wang, “Increased Recruitment of Endogenous Stem Cells and Chondrogenic Differentiation by a Composite Scaffold Containing Bone Marrow Homing Peptide for Cartilage Regeneration,” Theranostics, 8, 5039-5058 (2018).
B.T. Smith, A. Lu, E. Watson, M. Santoro, A.J. Melchiorri, E.C. Grosfeld, J.J.J.P. van den Beucken, J.A. Jansen, D.W. Scott, J.P. Fisher, and A.G. Mikos, “Incorporation of Fast Dissolving Glucose Porogens and Poly(Lactic-co-Glycolic Acid) Microparticles within Calcium Phosphate Cements for Bone Tissue Regeneration,” Acta Biomaterialia, 78, 341-350 (2018).
J. Lu, X. Sun, H. Yin, X. Shen, S. Yang, Y. Wang, W. Jiang, Y. Sun, L. Zhao, X. Sun, S. Lu, A.G. Mikos, J. Peng, and X. Wang, “A Neurotrophic Peptide-Functionalized Self-Assembling Peptide Nanofiber Hydrogel Enhances Rat Sciatic Nerve Regeneration,” Nano Res., 11, 4599-4613 (2018).
B. Akar, A.M. Tatara, A. Sutradhar, H.-Y. Hsiao, M. Miller, M.-H. Cheng, A.G. Mikos, and E.M. Brey, “Large Animal Models of an In Vivo Bioreactor for Engineering Vascularized Bone,” Tissue Eng. Part B: Reviews, 24, 317-325 (2018).
J. Yang, J.L. Guo, A.G. Mikos, C. He, and G. Cheng, “Material Processing and Design of Biodegradable Metal Matrix Composites for Biomedical Applications,” Ann. Biomed. Eng., 46, 1229-1240 (2018).
A.M. Tatara, D.P. Kontoyiannis, and A.G. Mikos, “Drug Delivery and Tissue Engineering to Promote Wound Healing in the Immunocompromised Host: Current Challenges and Future Directions,” Adv. Drug Deliv. Rev., 129, 319-329 (2018).
J. Zhou, X. Yang, W. Liu, C. Wang, Y. Shen, F. Zhang, H. Zhu, H. Sun, J. Chen, J. Lam, A.G. Mikos, and C. Wang, “Injectable OPF/Graphene Oxide Hydrogels Provide Mechanical Support and Enhance Cell Electrical Signaling after Implantation into Myocardial Infarct,” Theranostics, 8, 3317-3330 (2018).
A.M. Tatara, A.J. Rozich, P.D. Kontoyiannis, E. Watson, N.D. Albert, G.R. Bennett, and A.G. Mikos, “Econazole-Releasing Porous Space Maintainers for Fungal Periprosthetic Joint Infection,” J. Mater. Sci. Mater. Med., 29, 70 (2018).
L.K. Chim and A.G. Mikos, “Biomechanical Forces in Tissue Engineered Tumor Models,” Curr. Opin. Biomed. Eng., 6, 42-50 (2018).
J.E. Trachtenberg, M. Santoro, C. Williams III, C.M. Piard, B.T. Smith, J.K. Placone, B.A. Menegaz, E.R. Molina, S.-E. Lamhamedi-Cherradi, J.A. Ludwig, V.I. Sikavitsas, J.P. Fisher, and A.G. Mikos, “Effects of Shear Stress Gradients on Ewing Sarcoma Cells Using 3D Printed Scaffolds and Flow Perfusion,” ACS Biomater. Sci. Eng., 4, 347-356 (2018).
J. Yang, G.L. Koons, G. Cheng, L. Zhao, A.G. Mikos, and F. Cui, “A Review on the Exploitation of Biodegradable Magnesium-Based Composites for Medical Applications,” Biomed. Mater., 13, 022001 (8pp) (2018).
I. Lodoso-Torrecilla, N.A.P. van Gestel, L.A. Díaz-Gómez, E.C. Grosfeld, K. Laperre, J.G.C. Wolke, B.T. Smith, J.J. Arts, A.G. Mikos, J.A. Jansen, S. Hofmann, and J.J.J.P. van den Beucken, “Multimodal Pore Formation in Calcium Phosphate Cements,” J. Biomed. Mater. Res. Part A, 106A, 500-509 (2018).
2017
E. Watson, A.M. Tatara, D.P. Kontoyiannis, and A.G. Mikos, “Inherently Antimicrobial Biodegradable Polymers in Tissue Engineering,” ACS Biomater. Sci. Eng., 3, 1207-1220 (2017).
S.T. Heo, A.M. Tatara, C. Jiménez-Ortigosa, Y. Jiang, R.E. Lewis, J. Tarrand, F. Tverdek, N.D. Albert, P.E. Verweij, J.F. Meis, A.G. Mikos, D.S. Perlin, and D.P. Kontoyiannis, “Changes in In Vitro Susceptibility Patterns of Aspergillus to Triazoles and Correlation with Aspergillosis Outcome in a Tertiary Care Cancer Center, 1999-2015,” Clin. Infect. Dis., 65, 216-225 (2017).
E.J. Lee, B.K. Huh, S.N. Kim, J.Y. Lee, C.G. Park, A.G. Mikos, and Y.B. Choy, “Application of Materials as Medical Devices with Localized Drug Delivery Capabilities for Enhanced Wound Repair,” Progr. Mater. Sci., 89, 392-410 (2017).
L.G. Bracaglia, B.T. Smith, E. Watson, N. Arumugasaamy, A.G. Mikos, and J.P. Fisher, “3D Printing for the Design and Fabrication of Polymer-Based Gradient Scaffolds,” Acta Biomaterialia, 56, 3-13 (2017).
S. Wang, Y. Yang, Z. Zhao, X. Wang, A.G. Mikos, Z. Qiu, T. Song, X. Sun, L. Zhao, C. Zhang, and F. Cui, “Mineralized Collagen-Based Composite Bone Materials for Cranial Bone Regeneration in Developing Sheep,” ACS Biomater. Sci. Eng., 3, 1092-1099 (2017).
A.M. Tatara, E. Watson, T. Satish, D.W. Scott, D.P. Kontoyiannis, P.S. Engel, and A.G. Mikos, “Synthesis and Characterization of Diol-Based Unsaturated Polyesters: Poly(Diol Fumarate) and Poly(Diol Fumarate-co-Succinate),” Biomacromolecules, 18, 1724-1735 (2017).
Y. Du, H. Liu, Q. Yang, S. Wang, J. Wang, J. Ma, I. Noh, A.G. Mikos, and S. Zhang, “Selective Laser Sintering Scaffold with Hierarchical Architecture and Gradient Composition for Osteochondral Repair in Rabbits,” Biomaterials, 137, 37-48 (2017).
T. Guo, T.R. Holzberg, C.G. Lim, F. Gao, A. Gargava, J.E. Trachtenberg, A.G. Mikos, and J.P. Fisher, “3D Printing PLGA: A Quantitative Examination of the Effects of Polymer Composition and Printing Parameters on Print Resolution,” Biofabrication, 9, 024101 (11pp) (2017).
J.E. Trachtenberg, J.K. Placone, B.T. Smith, J.P. Fisher, and A.G. Mikos, “Extrusion-Based 3D Printing of Poly(Propylene Fumarate) Scaffolds with Hydroxyapatite Gradients,” J. Biomater. Sci., Polym. Ed., 28, 532-554 (2017).
B.T. Smith, M. Santoro, E.C. Grosfeld, S.R. Shah, J.J.J.P. van den Beucken, J.A. Jansen, and A.G. Mikos, “Incorporation of Fast Dissolving Glucose Porogens into an Injectable Calcium Phosphate Cement for Bone Tissue Engineering,” Acta Biomaterialia, 50, 68-77 (2017).
S.R. Shah, B.T. Smith, A.M. Tatara, E.R. Molina, E.J. Lee, T.C. Piepergerdes, B.A. Uhrig, R.E. Guldberg, G.N. Bennett, J.C. Wenke, and A.G. Mikos, “Effects of Local Antibiotic Delivery from Porous Space Maintainers on Infection Clearance and Induction of an Osteogenic Membrane in an Infected Bone Defect,” Tissue Eng. Part A, 23, 91-100 (2017).
M. Santoro, B.A. Menegaz, S.E. Lamhamedi-Cherradi, E.R. Molina, D. Wu, W. Priebe, J.A. Ludwig, and A.G. Mikos, “Modeling Stroma-Induced Drug Resistance in a Tissue-Engineered Tumor Model of Ewing Sarcoma,” Tissue Eng. Part A, 23, 80-89 (2017).
T.N. Vo, A.M. Tatara, M. Santoro, J.J.J.P. van den Beucken, S.C.G. Leeuwenburgh, J.A. Jansen, and A.G. Mikos, “Acellular Mineral Deposition within Injectable, Dual-Gelling Hydrogels for Bone Tissue Engineering,” J. Biomed. Mater. Res. Part A, 105A, 110-117 (2017).
2016
S.I. Simon, A.G. Mikos, and L.V. McIntire, “Fond Memories of our Mentor J. David Hellums, Annals of Biomedical Engineering,” Ann. Biomed. Eng., 44, 3157 (2016).
M. Santoro, S.R. Shah, J.L. Walker, and A.G. Mikos, “Poly(Lactic Acid) Nanofibrous Scaffolds for Tissue Engineering,” Adv. Drug Deliv. Rev., 107, 206-212 (2016).
A.M. Tatara, S.R. Shah, N. Demian, T. Ho, J. Shum, J.J.J.P. van den Beucken, J.A. Jansen, M.E. Wong, and A.G. Mikos, “Reconstruction of Large Mandibular Defects Using Autologous Tissues Generated from In Vivo Bioreactors,” Acta Biomaterialia, 45, 72-84 (2016).
J.E. Trachtenberg, J.K. Placone, B.T. Smith, C.M. Piard, M. Santoro, D.W. Scott, J.P. Fisher, and A.G. Mikos, “Extrusion-Based 3D Printing of Poly(Propylene Fumarate) in a Full-Factorial Design,” ACS Biomater. Sci. Eng., 2, 1771-1780 (2016).
S.-E. Lamhamedi-Cherradi, B.A. Menegaz, V. Ramamoorthy, D. Vishwamitra, Y. Wang, R.L. Maywald, A.S. Buford, I. Fokt, S. Skora, J. Wang, A. Naing, A.J. Lazar, E.M. Rohren, N.C. Daw, V. Subbiah, R.S. Benjamin, R. Ratan, W. Priebe, A.G. Mikos, H.M. Amin, and J.A. Ludwig, “IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma,” J. Natl. Cancer Inst., 108, djw182 (2016).
S.R. Shah, S. Young, J.L. Goldman, J.A. Jansen, M.E. Wong, and A.G. Mikos, “A Composite Critical-Size Rabbit Mandibular Defect for Evaluation of Craniofacial Tissue Regeneration,” Nature Protocols, 11, 1989-2009 (2016).
A.M. Tatara and A.G. Mikos, “Tissue Engineering in Orthopaedics,” J. Bone Joint Surg., 98, 1132-1139 (2016).
A.M. Tatara, A.G. Mikos, and D.P. Kontoyiannis, “Factors Affecting Patient Outcome in Primary Cutaneous Aspergillosis,” Medicine, 95, e3747 (2016).
T.N. Vo, Y. Tabata, and A.G. Mikos, “Effects of Cellular Parameters on the In Vitro Osteogenic Potential of Dual-Gelling Mesenchymal Stem Cell-Laden Hydrogels,” J. Biomater. Sci., Polym. Ed., 27, 1277-1290 (2016).
S. Lu, E.J. Lee, J. Lam, Y. Tabata, and A.G. Mikos, “Evaluation of Gelatin Microparticles as Adherent-Substrates for Mesenchymal Stem Cells in a Hydrogel Composite,” Ann. Biomed. Eng., 44, 1894-1907 (2016).
S.R. Shah, A.M. Tatara, J. Lam, S. Lu, D.W. Scott, G.N. Bennett, J.J.J.P. van den Beucken, J.A. Jansen, M.E. Wong, and A.G. Mikos, “Polymer-Based Local Antibiotic Delivery for Prevention of Polymicrobial Infection in Contaminated Mandibular Implants,” ACS Biomater. Sci. Eng., 2, 558-566 (2016).
J. Lam, E.C. Clark, E.L.S. Fong, E.J. Lee, S. Lu, Y. Tabata, and A.G. Mikos, “Data Describing the Swelling Behavior and Cytocompatibility of Biodegradable Polyelectrolyte Hydrogels Incorporating Poly(L-Lysine) for Applications in Cartilage Tissue Engineering,” Data-in-Brief, 7, 614-619 (2016).
J. Lam, E.C. Clark, E.L.S. Fong, E.J. Lee, S. Lu, Y. Tabata, and A.G. Mikos, “Evaluation of Cell-Laden Polyelectrolyte Hydrogels Incorporating Poly(L-Lysine) for Applications in Cartilage Tissue Engineering,” Biomaterials, 83, 332-346 (2016).
T.N. Vo, S.R. Shah, S. Lu, A.M. Tatara, E.J. Lee, T.T. Roh, Y. Tabata, and A.G. Mikos, “Injectable Dual-Gelling Cell-Laden Composite Hydrogels for Bone Tissue Engineering,” Biomaterials, 83, 1-11 (2016).
A.M. Tatara and A.G. Mikos, “2015 Lifetime Achievement Award of Tissue Engineering and Regenerative Medicine International Society-Americas: Antonios G. Mikos, PhD,” Tissue Eng. Part A, 22, 1-2 (2016).
P.M. Mountziaris, S.R. Shah, J. Lam, G.N. Bennett, and A.G. Mikos, “A Rapid, Flexible Method for Incorporating Controlled Antibiotic Release into Porous Polymethylmethacrylate Space Maintainers for Craniofacial Reconstruction,” Biomater. Sci., 4, 121-129 (2016).
E.L.S. Fong, X. Wan, J. Yang, M. Morgado, A.G. Mikos, D.A. Harrington, N.M. Navone, and M.C. Farach-Carson, “A 3D In Vitro Model of Patient-Derived Prostate Cancer Xenograft for Controlled Interrogation of In Vivo Tumor-Stromal Interactions,” Biomaterials, 77, 164-172 (2016).
2015
B.T. Smith, J. Shum, M.E. Wong, A.G. Mikos, and S. Young, “Bone Tissue Engineering Challenges in Oral and Maxillofacial Surgery,” Adv. Exp. Med. Biol., 881, 57-78 (2015).
S. Lu, J. Lam, J.E. Trachtenberg, E.J. Lee, H. Seyednejad, J.J.J.P. van den Beucken, Y. Tabata, F.K. Kasper, D.W. Scott, M.E. Wong, J.A. Jansen, and A.G. Mikos, “Correlation between the Repair of Cartilage and Subchondral Bone in an Osteochondral Defect Using Bilayered, Biodegradable Hydrogel Composites,” Tissue Eng. Part C: Methods, 21, 1216-1225 (2015).
E.R. Molina, B.T. Smith, S.R. Shah, H. Shin, and A.G. Mikos, “Immunomodulatory Properties of Stem Cells and Bioactive Molecules for Tissue Engineering,” J. Controlled Release, 219, 107-118 (2015).
B.M. Watson, T.N. Vo, P.S. Engel, and A.G. Mikos, “Biodegradable, In Situ-Forming Cell-Laden Hydrogel Composites of Hydroxyapatite Nanoparticles for Bone Regeneration,” Ind. Eng. Chem. Res., 54, 10206-10211 (2015).
A.G. Mikos, P.C. Johnson, J.P. Fisher, and J.A. Jansen, “The Maturation of Tissue Engineering,” Tissue Eng. Part A, 21, 2473-2475 (2015).
B.N. Sathy, B.M. Watson, L.A. Kinard, P.P. Spicer, R.L. Dahlin, A.G. Mikos, and S. Nair, “Bone Tissue Engineering with Multilayered Scaffolds – Part II: Combining Vascularization with Bone Formation in Critical-Sized Bone Defect,” Tissue Eng. Part A, 21, 2495-2503 (2015).
B.N. Sathy, U. Mony, D. Menon, V.K. Baskaran, A.G. Mikos, and S. Nair, “Bone Tissue Engineering with Multilayered Scaffolds – Part I: An Approach for Vascularizing Engineered Constructs In Vivo,” Tissue Eng. Part A, 21, 2480-2494 (2015).
S.K. Madhurakkat Perikamana, J. Lee, Y.B. Lee, Y.M. Shin, E.J. Lee, A.G. Mikos, and H. Shin, “Materials from Mussel-Inspired Chemistry for Cell and Tissue Engineering Applications,” Biomacromolecules, 16, 2541-2555 (2015).
M. Santoro, S.E. Lamhamedi-Cherradi, B.A. Menegaz, J.A. Ludwig, and A.G. Mikos, “Flow Perfusion Effects on Three-Dimensional Culture and Drug Sensitivity of Ewing Sarcoma,” Proceed. Natl. Acad. Sci. USA, 112, 10304-10309 (2015).
A.M. Tatara, S.R. Shah, C.E. Livingston, and A.G. Mikos, “Infected Animal Models for Tissue Engineering,” Methods, 84, 17-24 (2015).
B.M. Watson, T.N. Vo, A.M. Tatara, S.R. Shah, D.W. Scott, P.S. Engel, and A.G. Mikos, “Biodegradable, Phosphate-Containing, Dual-Gelling Macromers for Cellular Delivery in Bone Tissue Engineering,” Biomaterials, 67, 286-296 (2015).
J. Lam, S. Lu, F.K. Kasper, and A.G. Mikos, “Strategies for Controlled Delivery of Biologics for Cartilage Repair,” Adv. Drug Deliv. Rev., 84, 123-134 (2015).
A.M. Tatara, S.R. Shah, M. Sotoudeh, A.M. Henslee, M.E. Wong, A. Ratcliffe, F.K. Kasper, and A.G. Mikos, “Effects of Electron Beam Sterilization on Mechanical Properties of a Porous Polymethylmethacrylate Space Maintenance Device,” J. Med. Dev., 9, 024501-1-024501-4 (2015).
A.M. Tatara, J.D. Kretlow, P.P. Spicer, S. Lu, J. Lam, W. Liu, Y. Cao, G. Liu, J.D. Jackson, J.J. Yoo, A. Atala, J.J.J.P. van den Beucken, J.A. Jansen, F.K. Kasper, T. Ho, N. Demian, M.J. Miller, M.E. Wong, and A.G. Mikos, “Autologously Generated Tissue-Engineered Bone Flaps for Reconstruction of Large Mandibular Defects in an Ovine Model,” Tissue Eng. Part A, 21, 1520-1528 (2015).
T.N. Vo, A.K. Ekenseair, P.P. Spicer, B.M. Watson, S.N. Tzouanas, T.T. Roh, and A.G. Mikos, “In Vitro and In Vivo Evaluation of Self-Mineralization and Biocompatibility of Injectable, Dual-Gelling Hydrogels for Bone Tissue Engineering,” J. Controlled Release, 205, 25-34 (2015).
A.M. Henslee, D.M. Yoon, B.Y. Lu, J. Yu, A.A. Arango, L.P. Marruffo, L. Seng, T.D. Anver, H. Ather, M.B. Nair, S.O. Piper, N. Demian, M.E.K. Wong, F.K. Kasper, and A.G. Mikos, “Characterization of an Injectable, Degradable Polymer for Mechanical Stabilization of Mandibular Fractures,” J. Biomed. Mater. Res. Part B: Appl. Biomater., 103B, 529-538 (2015).
J.E. Trachtenberg, T.N. Vo, and A.G. Mikos, “Pre-Clinical Characterization of Tissue Engineering Constructs for Bone and Cartilage Regeneration,” Ann. Biomed. Eng., 43, 681-696 (2015).
S.R. Shah, C.A. Werlang, F.K. Kasper, and A.G. Mikos, “Novel Applications of Statins for Bone Regeneration,” Natl. Sci. Rev., 2, 85-99 (2015).
L. Wang, S. Lu, J. Lam, F.K. Kasper, and A.G. Mikos, “Fabrication of Cell-Laden Macroporous Biodegradable Hydrogels with Tunable Porosities and Pore Sizes,” Tissue Eng. Part C: Methods, 21, 263-273 (2015).
A.M. Henslee, S.R. Shah, M.E. Wong, A.G. Mikos, and F.K. Kasper, “Degradable, Antibiotic Releasing Poly(Propylene Fumarate)-Based Constructs for Craniofacial Space Maintenance Applications,” J. Biomed. Mater. Res. Part A, 103A, 1485-1497 (2015).
2014
K.M. Hubka, R.L. Dahlin, V.V. Meretoja, F.K. Kasper, and A.G. Mikos, “Enhancing Chondrogenic Phenotype for Cartilage Tissue Engineering: Monoculture and Coculture of Articular Chondrocytes and Mesenchymal Stem Cells,” Tissue Eng. Part B: Reviews, 20, 641-654 (2014).
S.-E. Lamhamedi-Cherradi, M. Santoro, V. Ramammoorthy, B.A. Menegaz, G. Bartholomeusz, L.R. Iles, H.M. Amin, A.J. Livingston, A.G. Mikos, and J.A. Ludwig, “3D Tissue-Engineered Model of Ewing’s Sarcoma,” Adv. Drug Deliv. Rev., 79-80, 155-171 (2014).
A.M. Tatara, M.E. Wong, and A.G. Mikos, “In Vivo Bioreactors for Mandibular Reconstruction,” J. Dent. Res., 93, 1196-1202 (2014).
R.L. Dahlin, V.V. Meretoja, M. Ni, F.K. Kasper, and A.G. Mikos, “Chondrogenic Phenotype of Articular Chondrocytes in Monoculture and Co-Culture with Mesenchymal Stem Cells in Flow Perfusion,” Tissue Eng. Part A, 20, 2883-2891 (2014).
S.R. Shah, A.M. Henslee, P.P. Spicer, S. Yokota, S. Petrichenko, S. Allahabadi, G.N. Bennett, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Effects of Antibiotic Physicochemical Properties on their Release Kinetics from Biodegradable Polymer Microparticles,” Pharm. Res., 31, 3379-3389 (2014).
A.W.G. Nijhuis, S. Takemoto, M.R. Nejadnik, Y. Li, X. Yang, D.A. Ossipov, J. Hilborn, A.G. Mikos, M. Yoshinari, J.A. Jansen, and S.C.G. Leeuwenburgh, “Rapid Screening of Mineralization Capacity of Biomaterials by Means of Quantification of Enzymatically Deposited Calcium Phosphate,” Tissue Eng. Part C: Methods, 20, 838-850 (2014).
J.E. Trachtenberg, P.M. Mountziaris, J.S. Miller, M. Wettergreen, F.K. Kasper, and A.G. Mikos, “Open-Source Three-Dimensional Printing of Biodegradable Polymer Scaffolds for Tissue Engineering,” J. Biomed. Mater. Res. Part A, 102A, 4326-4335 (2014).
L.A. Kinard, R.L. Dahlin, J. Lam, S. Lu, E.J. Lee, F.K. Kasper, and A.G. Mikos, “Synthetic Biodegradable Hydrogel Delivery of Demineralized Bone Matrix for Bone Augmentation in a Rat Model,” Acta Biomaterialia, 10, 4574-4582 (2014).
C.J. Needham, S.R. Shah, R.L. Dahlin, L.A. Kinard, J. Lam, B.M. Watson, S. Lu, F.K. Kasper, and A.G. Mikos, “Osteochondral Tissue Regeneration Through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2,” Acta Biomaterialia, 10, 4103-4112 (2014).
S. Lu, J. Lam, J.E. Trachtenberg, E.J. Lee, H. Seyednejad, J.J.J.P. van den Beucken, Y. Tabata, M.E. Wong, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Dual Growth Factor Delivery from Bilayered, Biodegradable Hydrogel Composites for Spatially-Guided Osteochondral Tissue Repair,” Biomaterials, 35, 8829-8839 (2014).
J. Lam, S. Lu, E.J. Lee, J.E. Trachtenberg, V.V. Meretoja, R.L. Dahlin, J.J.J.P. van den Beucken, Y. Tabata, M.E. Wong, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Osteochondral Defect Repair Using Bilayered Hydrogels Encapsulating Both Chondrogenically and Osteogenically Pre-Differentiated Mesenchymal Stem Cells in a Rabbit Model,” Osteoarthritis Cartilage, 22, 1291-1300 (2014).
J. Lam, K. Kim, S. Lu, Y. Tabata, D.W. Scott, A.G. Mikos, and F.K. Kasper, “A Factorial Analysis of the Combined Effects of Hydrogel Fabrication Parameters on the In Vitro Swelling and Degradation of Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels,” J. Biomed. Mater. Res. Part A, 102A, 3477-3487 (2014).
M. Santoro, A.M. Tatara, and A.G. Mikos, “Gelatin Carriers for Drug and Cell Delivery in Tissue Engineering,” J. Controlled Release, 190, 210-218 (2014).
E.L.S. Fong, M. Martinez, J. Yang, A.G. Mikos, N.M. Navone, D.A. Harrington, and M.C. Farach-Carson, “Hydrogel-Based 3D Model of Patient-Derived Prostate Xenograft Tumors Suitable for Drug Screening,” Mol. Pharm., 11, 2040-2050 (2014).
R.L. Dahlin, J.G. Gershovich, F.K. Kasper, and A.G. Mikos, “Flow Perfusion Co-Culture of Human Mesenchymal Stem Cells and Endothelial Cells on Biodegradable Polymer Scaffolds,” Ann. Biomed. Eng., 42, 1381-1390 (2014).
R.L. Dahlin, L.A. Kinard, J. Lam, C.J. Needham, S. Lu, F.K. Kasper, and A.G. Mikos, “Articular Chondrocytes and Mesenchymal Stem Cells Seeded on Biodegradable Scaffolds for the Repair of Cartilage in a Rat Osteochondral Defect Model,” Biomaterials, 35, 7460-7469 (2014).
B.M. Watson, F.K. Kasper, P.S. Engel, and A.G. Mikos, “Synthesis and Characterization of Injectable, Biodegradable, Phosphate-Containing, Chemically Cross-Linkable, Thermoresponsive Macromers for Bone Tissue Engineering,” Biomacromolecules, 15, 1788-1796 (2014).
L.A. Kinard, R.L. Dahlin, A.M. Henslee, P.P. Spicer, C.-Y. Chu, Y. Tabata, J.J.J.P. van den Beucken, J.A. Jansen, S. Young, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Tissue Response to Composite Hydrogels for Vertical Bone Augmentation in the Rat,” J. Biomed. Mater. Res. Part A, 102A, 2079-2088 (2014).
V.V. Meretoja, R.L. Dahlin, S. Wright, F.K. Kasper, and A.G. Mikos, “Articular Chondrocyte Redifferentiation in 3D Co-Cultures with Mesenchymal Stem Cells,” Tissue Eng. Part C: Methods, 20, 514-523 (2014).
T.N. Vo, J.E. Trachtenberg, and A.G. Mikos, “In Vitro Techniques for Biomaterial Evaluation in Bone and Cartilage Tissue Engineering,” Regener. Med., J. Japan. Soc. Regener. Med., 13, 125-149 (2014).
A.M. Henslee, P.P. Spicer, S.R. Shah, A.M. Tatara, F.K. Kasper, A.G. Mikos, and M.E. Wong, “Use of Porous Space Maintainers in Staged Mandibular Reconstruction,” Oral Maxillofac. Surg. Clin. North Am., 26, 143-149 (2014).
E.J. Levorson, P.M. Mountziaris, O. Hu, F.K. Kasper, and A.G. Mikos, “Cell-Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 1: Investigation of Cocultures and Seeding Densities for Improved Extracellular Matrix Deposition,” Tissue Eng. Part C: Methods, 20, 340-357 (2014).
E.J. Levorson, O. Hu, P.M. Mountziaris, F.K. Kasper, and A.G. Mikos, “Cell-Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 2: Construct Devitalization and Determination of Chondroinductive Capacity,” Tissue Eng. Part C: Methods, 20, 358-372 (2014).
E.J. Levorson, M. Santoro, F.K. Kasper, and A.G. Mikos, “Direct and Indirect Co-Culture of Chondrocytes and Mesenchymal Stem Cells for the Generation of Polymer/Extracellular Matrix Hybrid Constructs,” Acta Biomaterialia, 10, 1824-1835 (2014).
S.N. Tzouanas, A.K. Ekenseair, F.K. Kasper, and A.G. Mikos, “Mesenchymal Stem Cell and Gelatin Microparticle Encapsulation in Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering,” J. Biomed. Mater. Res. Part A, 102A, 1222-1230 (2014).
B.M. Watson, F.K. Kasper, and A.G. Mikos, “Phosphorous-Containing Polymers for Regenerative Medicine,” Biomed. Mater., 9, 025014 (10pp) (2014).
E.J. Lee, F.K. Kasper, and A.G. Mikos, “Biomaterials for Tissue Engineering,” Ann. Biomed. Eng., 42, 323-337 (2014).
J. Ma, F. Yang, S.K. Both, M. Kersten-Niessen, M. Bongio, J. Pan, F.-Z. Cui, F.K. Kasper, A.G. Mikos, J.A. Jansen, and J.J.J.P. van den Beucken, “Comparison of Cell-Loading Methods in Hydrogel Systems,” J. Biomed. Mater. Res. Part A, 102A, 935-946 (2014).
E.J. Lee, J.J. Tabor, and A.G. Mikos, “Leveraging Synthetic Biology for Tissue Engineering Applications,” Inflamm. Regener., 34, 15-22 (2014).
J. Lam, S. Lu, Y. Tabata, A.G. Mikos, and F.K. Kasper, “Generation of Osteochondral Tissue Constructs with Chondrogenically and Osteogenically Pre-differentiated Mesenchymal Stem Cells Encapsulated in Bilayered Hydrogels,” Acta Biomaterialia, 10, 1112-1123 (2014).
T.N. Vo, A.K. Ekenseair, F.K. Kasper, and A.G. Mikos, “Synthesis, Physicochemical Characterization, and Cytocompatibility of Bioresorbable, Dual-Gelling Injectable Hydrogels,” Biomacromolecules, 15, 132-142 (2014).
E.L. Fong, M. Santoro, M.C. Farach-Carson, F.K. Kasper, and A.G. Mikos, “Tissue Engineering Perfusable Cancer Models,” Curr. Opin. Chem. Eng., 3, 112-117 (2014).
C.G. Ambrose, T.A. Clyburn, J. Mika, G.R. Gogola, H.B. Kaplan, A. Wanger, and A.G. Mikos, “Evaluation of Antibiotic-Impregnated Microspheres for the Prevention of Implant-Associated Orthopaedic Infections,” J. Bone Joint Surg., 96, 128-134 (2014).
C.J. Needham, S.R. Shah, P.M. Mountziaris, F.K. Kasper, and A.G. Mikos, “Modulation of Polyplex Release from Biodegradable Microparticles through Poly(Ethylenimine) Modification and Varying Loading Concentration,” Pharm. Res., 31, 77-85 (2014).
R.L. Dahlin, M. Ni, V.V. Meretoja, F.K. Kasper, and A.G. Mikos, “TGF-ß3-Induced Chondrogenesis in Co-Cultures of Chondrocytes and Mesenchymal Stem Cells on Biodegradable Scaffolds,” Biomaterials, 35, 123-132 (2014).
2013
S.R. Shah, F.K. Kasper, and A.G. Mikos, “Perspectives on the Prevention and Treatment of Infection for Orthopedic Tissue Engineering Applications,” Chin. Sci. Bull., 58, 4342-4348 (2013).
J.G. Gershovich, R.L. Dahlin, F.K. Kasper, and A.G. Mikos, “Enhanced Osteogenesis in Cocultures with Human Mesenchymal Stem Cells and Endothelial Cells on Polymeric Microfiber Scaffolds,” Tissue Eng. Part A, 19, 2565-2576 (2013).
M.R. Nejadnik, X. Yang, T. Mimura, Z. Tahmasebi Birgani, P. Habibovic, K. Itatani, J.A. Jansen, J. Hilborn, D.A. Ossipov, A.G. Mikos, and S.C.G. Leeuwenburgh, “Calcium-Mediated Secondary Cross-Linking of Bisphosphonated Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels,” Macromol. Biosci., 13, 1308-1313 (2013).
E.J. Rivera, L.A. Tran, M. Hernandez-Rivera, D. Yoon, A.G. Mikos, I.A. Rusakova, B.Y. Cheong, M.G. Cabreira-Hansen, J.T. Willerson, E.C. Perin, and L.J. Wilson, “Bismuth@US-Tubes as a Potential Contrast Agent for X-Ray Imaging Applications,” J. Mater. Chem. B, 1, 4792-4800 (2013).
J.E. Trachtenberg, P.M. Mountziaris, F.K. Kasper, and A.G. Mikos, “Fiber-Based Composite Tissue Engineering Scaffolds for Drug Delivery,” Israel J. Chem., 53, 646-654 (2013).
P.P. Spicer, S.R. Shah, A.M. Henslee, B.M. Watson, L.A. Kinard, J.D. Kretlow, K. Bevil, L. Kattchee, G.N. Bennett, N. Demian, K. Mende, C.K. Murray, J.A. Jansen, M.E. Wong, A.G. Mikos, and F.K. Kasper, “Evaluation of Antibiotic Releasing Porous Polymethylmethacrylate Space Maintainers in an Infected Composite Tissue Defect Model,” Acta Biomaterialia, 9, 8832-8839 (2013).
M. Bongio, M.R. Nejadnik, F.K. Kasper, A.G. Mikos, J.A. Jansen, S.C.G. Leeuwenburgh, and J.J.J.P. van den Beucken, “Development of an In Vitro Confinement Test to Predict the Clinical Handling of Polymer-Based Injectable Bone Substitutes,” Polym. Test., 32, 1379-1384 (2013).
P.M. Mountziaris, E.D. Lehman, I. Mountziaris, D.C. Sing, F.K. Kasper, and A.G. Mikos, “Effect of Temporally Patterned TNF-a Delivery on In Vitro Osteogenic Differentiation of Mesenchymal Stem Cells Cultured on Biodegradable Polymer Scaffolds,” J. Biomater. Sci., Polym. Ed., 24, 1794-1813 (2013).
L.A. Kinard, C.-Y. Chu, Y. Tabata, F.K. Kasper, and A.G. Mikos, “Bone Morphogenetic Protein-2 Release from Composite Hydrogels of Oligo(Poly(Ethylene Glycol) Fumarate) and Gelatin,” Pharm. Res., 30, 2332-2343 (2013).
G. Lalwani, A.M. Henslee, B. Farshid, P. Parmar, L. Lin, Y.-X. Qin, F.K. Kasper, A.G. Mikos, and B. Sitharaman, “Tungsten Disulfide Nanotubes Reinforced Biodegradable Polymers for Bone Tissue Engineering,” Acta Biomaterialia, 9, 8365-8373 (2013).
R.L. Dahlin, V.V. Meretoja, M. Ni, F.K. Kasper, and A.G. Mikos, “Hypoxia and Flow Perfusion Modulate Proliferation and Gene Expression of Articular Chondrocytes on Porous Scaffolds,” AIChE J., 59, 3158-3166 (2013).
C.T. Lim, X. Ren, M.H. Afizah, S. Tarigan-Panjaitan, Z. Yang, Y. Wu, K.S. Chian, A.G. Mikos, and J.H. Hui, “Repair of Osteochondral Defects with Rehydrated Freeze-Dried Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels Seeded with Bone Marrow Mesenchymal Stem Cells in a Porcine Model,” Tissue Eng. Part A, 19, 1852-1861 (2013).
S.R. Shah, A.M. Tatara, R.N. D’Souza, A.G. Mikos, and F.K. Kasper, “Evolving Strategies for Preventing Biofilm on Implantable Materials,” Materials Today, 16, 177-182 (2013).
M. Bongio, M.R. Nejadnik, Z.T. Birgani, P. Habibovic, L.A. Kinard, F.K. Kasper, A.G. Mikos, J.A. Jansen, S.C.G. Leeuwenburgh, and J.J.J.P. van den Beucken, “In Vitro and In Vivo Enzyme-Mediated Biomineralization of Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels,” Macromol. Biosci., 13, 777-788 (2013).
J.H. Hui, X. Ren, M.H. Afizah, K.S. Chian, and A.G. Mikos, “Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogel Enhances Osteochondral Repair in Porcine Femoral Condyle Defects,” Clin. Orthop. Rel. Res., 471, 1174-1185 (2013).
L. Wang, D.M. Yoon, P.P. Spicer, A.M. Henslee, D.W. Scott, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Characterization of Porous Polymethylmethacrylate Space Maintainers for Craniofacial Reconstruction,” J. Biomed. Mater. Res. Part B: Appl. Biomater., 101B, 813-825 (2013).
E.L.S. Fong, S.-E. Lamhamedi-Cherradi, E. Burdett, V. Ramamoorthy, A.J. Lazar, F.K. Kasper, M.C. Farach-Carson, D. Vishwamitra, E.G. Demicco, B.A. Menegaz, H.M. Amin, A.G. Mikos, and J.A. Ludwig, “Modeling Ewing Sarcoma Tumors In Vitro with 3D Scaffolds,” Proceed. Natl. Acad. Sci. USA, 110, 6500-6505 (2013).
K. Kim, J. Lam, S. Lu, P.P. Spicer, A. Lueckgen, Y. Tabata, M.E. Wong, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Osteochondral Tissue Regeneration Using a Bilayered Composite Hydrogel with Modulating Dual Growth Factor Release Kinetics in a Rabbit Model,” J. Controlled Release, 168, 166-178 (2013).
G. Lalwani, A.M. Henslee, B. Farshid, L. Lin, F.K. Kasper, Y.-X. Qin, A.G. Mikos, and B. Sitharaman, “Two-Dimensional Nanostructure-Reinforced Biodegradable Polymeric Nanocomposites for Bone Tissue Engineering,” Biomacromolecules, 14, 900-909 (2013).
R.A. Thibault, A.G. Mikos, and F.K. Kasper, “Osteogenic Differentiation of Mesenchymal Stem Cells on Demineralized and Devitalized Biodegradable Polymer and Extracellular Matrix Hybrid Constructs,” J. Biomed. Mater. Res. Part A, 101A, 1225-1236 (2013).
V.V. Meretoja, R.L. Dahlin, S. Wright, F.K. Kasper, and A.G. Mikos, “The Effect of Hypoxia on the Chondrogenic Differentiation of Co-Cultured Articular Chondrocytes and Mesenchymal Stem Cells in Scaffolds,” Biomaterials, 34, 4266-4273 (2013).
A.K. Ekenseair, F.K. Kasper, and A.G. Mikos, “Perspectives on the Interface of Drug Delivery and Tissue Engineering,” Adv. Drug Deliv. Rev., 65, 89-92 (2013).
M. Bongio, J.J.J.P. van den Beucken, M.R. Nejadnik, Z.T. Birgani, P. Habibovic, L.A. Kinard, F.K. Kasper, A.G. Mikos, S.C.G. Leeuwenburgh, and J.A. Jansen, “Subcutaneous Tissue Response and Osteogenic Performance of Calcium Phosphate Nanoparticle-Enriched Hydrogels in the Tibial Medullary Cavity of Guinea Pigs,” Acta Biomaterialia, 9, 5464-5474 (2013).
E.J. Levorson, P.R. Sreerekha, K.P. Chennazhi, F.K. Kasper, S.V. Nair, and A.G. Mikos, “Fabrication and Characterization of Multiscale Electrospun Scaffolds for Cartilage Regeneration,” Biomed. Mater., 8, 014103 (11pp) (2013).
R.A. Thibault, A.G. Mikos, and F.K. Kasper, “Scaffold/Extracellular Matrix Hybrid Constructs for Bone-Tissue Engineering,” Adv. Healthcare Mater., 2, 13-24 (2013).
2012
A.A. Appel, J.C. Larson, S. Somo, Z. Zhong, P.P. Spicer, F.K. Kasper, A.B. Garson, A.M. Zysk, A.G. Mikos, M.A. Anastasio, and E.M. Brey, “Imaging of Poly(a-Hydroxy-Ester) Scaffolds with X-Ray Phase-Contrast Microcomputed Tomography,” Tissue Eng. Part C: Methods, 18, 859-865 (2012).
A. Atala, F. K. Kasper, A. G. Mikos, “Engineering Complex Tissues,” Sci. Transl. Med. 4, 160rv12 (2012).
R.L. Dahlin, V.V. Meretoja, M. Ni, F.K. Kasper, and A.G. Mikos, “Design of a High-Throughput Flow Perfusion Bioreactor System for Tissue Engineering,” Tissue Eng. Part C: Methods, 18, 817-820 (2012).
P.P. Spicer, J.D. Kretlow, S. Young, J.A. Jansen, F.K. Kasper, and A.G. Mikos, “Evaluation of Bone Regeneration Using the Rat Critical Size Calvarial Defect,” Nature Protocols, 7, 1918-1929 (2012).
E.L.S. Fong, B.M. Watson, F.K. Kasper, and A.G. Mikos, “Building Bridges: Leveraging Interdisciplinary Collaborations in the Development of Biomaterials to Meet Clinical Needs,” Adv. Mater., 24, 4995-5013 (2012).
A.K. Ekenseair, K.W.M. Boere, S.N. Tzouanas, T.N. Vo, F.K. Kasper, and A.G. Mikos, “Structure-Property Evaluation of Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering,” Biomacromolecules, 13, 2821-2830 (2012).
T.E.L. Douglas, P.B. Messersmith, S. Chasan, A.G. Mikos, E.L.W. de Mulder, G. Dickson, D. Schaubroeck, L. Balcaen, F. Vanhaecke, P. Dubruel, J.A. Jansen, and S.C.G. Leeuwenburgh, “Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase,” Macromol. Biosci., 12, 1077-1089 (2012).
P.M. Mountziaris, S.N. Tzouanas, D.C. Sing, P.R. Kramer, F.K. Kasper, and A.G. Mikos, “Intra-Articular Controlled Release of Anti-Inflammatory siRNA with Biodegradable Polymer Microparticles Ameliorates Temporomandibular Joint Inflammation,” Acta Biomaterialia, 8, 3552-3560 (2012).
T.N. Vo, F.K. Kasper, and A.G. Mikos, “Strategies for Controlled Delivery of Growth Factors and Cells for Bone Regeneration,” Adv. Drug Deliv. Rev., 64, 1292-1309 (2012).
A.M. Henslee, D.-H. Gwak, A.G. Mikos, and F.K. Kasper, “Development of a Biodegradable Bone Cement for Craniofacial Applications,” J. Biomed. Mater. Res. Part A, 100A, 2252-2259 (2012).
A.K. Ekenseair, K.W.M. Boere, S.N. Tzouanas, T.N. Vo, F.K. Kasper, and A.G. Mikos, “Synthesis and Characterization of Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering,” Biomacromolecules, 13, 1908-1915 (2012).
V.V. Meretoja, R.L. Dahlin, F.K. Kasper, and A.G. Mikos, “Enhanced Chondrogenesis in Co-Cultures with Articular Chondrocytes and Mesenchymal Stem Cells,” Biomaterials, 33, 6362-6369 (2012).
L.A. Kinard, F.K. Kasper, and A.G. Mikos, “Synthesis of Oligo(Poly(Ethylene Glycol) Fumarate),” Nature Protocols, 7, 1219-1227 (2012).
H. Wang, Z. Liu, D. Li, X. Guo, F.K. Kasper, C. Duan, J. Zhou, A.G. Mikos, and C. Wang, “Injectable Biodegradable Hydrogels for Embryonic Stem Cell Transplantation: Improved Cardiac Remodeling and Function of Myocardial Infarction,” J. Cell. Mol. Med., 16, 1310-1320 (2012).
G. Somma, H.M. Alger, R.M. McGuire, J.D. Kretlow, F.R. Ruiz, S.A. Yatsenko, P. Stankiewicz, W. Harrison, E. Funk, A. Bergamaschi, J.S. Oghalai, A.G. Mikos, P.A. Overbeek, and F.A. Pereira, “Head Bobber: An Insertional Mutation Causes Inner Ear Defects, Hyperactive Circling, and Deafness,” J. Assoc. Res. Otolaryngol., 13, 335-349 (2012).
C.J. Needham, A.K. Williams, S.A. Chew, F.K. Kasper, and A.G. Mikos, “Engineering a Polymeric Gene Delivery Vector Based on Poly(Ethylenimine) and Hyaluronic Acid,” Biomacromolecules, 13, 1429-1437 (2012).
D. Dean, J. Wallace, A. Siblani, M.O. Wang, K. Kim, A.G. Mikos, and J.P. Fisher, “Continuous Digital Light Processing (cDLP): Highly Accurate Additive Manufacturing of Tissue Engineered Bone Scaffolds,” Virt. Phys. Prototyp., 7, 13-24 (2012).
P.K. Avti, S. Hu, C. Favazza, A.G. Mikos, J.A. Jansen, K.R. Shroyer, L.V. Wang, and B. Sitharaman, “Detection, Mapping, and Quantification of Single Walled Carbon Nanotubes in Histological Specimens with Photoacoustic Microscopy,” PLoS ONE, 7(4), e35064 (2012).
M.R. Nejadnik, A.G. Mikos, J.A. Jansen, and S.C.G. Leeuwenburgh, “Facilitating the Mineralization of Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogel by Incorporation of Hydroxyapatite Nanoparticles,” J. Biomed. Mater. Res. Part A, 100A, 1316-1323 (2012).
P.M. Mountziaris, S.N. Tzouanas, and A.G. Mikos, “The Interplay of Bone-Like Extracellular Matrix and TNF-α Signaling on In Vitro Osteogenic Differentiation of Mesenchymal Stem Cells,” J. Biomed. Mater. Res. Part A, 100A, 1097-1106 (2012).
P.P. Spicer, J.D. Kretlow, A.M. Henslee, M. Shi, S. Young, N. Demian, J.A. Jansen, M.E. Wong, A.G. Mikos, and F.K. Kasper, “In Situ Formation of Porous Space Maintainers in a Composite Tissue Defect,” J. Biomed. Mater. Res. Part A, 100A, 827-833 (2012).
A.M. Martins, J.D. Kretlow, A.R. Costa-Pinto, P.B. Malafaya, E.M. Fernandes, N.M. Neves, C.M. Alves, A.G. Mikos, F.K. Kasper, and R.L. Reis, “Gradual Pore Formation in Natural Origin Scaffolds Throughout Subcutaneous Implantation,” J. Biomed. Mater. Res. Part A, 100A, 599-612 (2012).
S. Srinivasan, R. Jayakumar, K.P. Chennazhi, E.J. Levorson, A.G. Mikos, and S.V. Nair, “Multiscale Fibrous Scaffolds in Regenerative Medicine,” Adv. Polym. Sci., 246, 1-20 (2012).
2011
C. Nguyen, S. Young, J.D. Kretlow, A.G. Mikos, and M. Wong, “Surface Characteristics of Biomaterials Used for Space Maintenance in a Mandibular Defect: A Pilot Animal Study,” J. Oral Maxillofac. Surg., 69, 11-18 (2011).
M. van der Zande, B. Sitharaman, X.F. Walboomers, L. Tran, J.S. Ananta, A. Veltien, L.J. Wilson, J.I. Álava, A. Heerschap, A.G. Mikos, and J.A. Jansen, “In Vivo Magnetic Resonance Imaging of the Distribution Pattern of Gadonanotubes Released from a Degrading Poly(Lactic-co-Glycolic Acid) Scaffold,” Tissue Eng. Part C: Methods, 17, 19-26 (2011).
K. Kim, D. Dean, A. Lu, A.G. Mikos, and J.P. Fisher, “Early Osteogenic Signal Expression of Rat Bone Marrow Stromal Cells Is Influenced by Both Hydroxyapatite Nanoparticle Content and Initial Cell Seeding Density in Biodegradable Nanocomposite Scaffolds,” Acta Biomaterialia, 7, 1249-1264 (2011).
L. Klouda, K.R. Perkins, B.M. Watson, M.C. Hacker, S.J. Bryant, R.M. Raphael, F.K. Kasper, and A.G. Mikos, “Thermoresponsive, In Situ Crosslinkable Hydrogels Based on N-Isopropylacrylamide: Fabrication, Characterization and Mesenchymal Stem Cell Encapsulation,” Acta Biomaterialia, 7, 1460-1467 (2011).
H. Liao, X.F. Walboomers, W.J.E.M. Habraken, Z. Zhang, Y. Li, D.W. Grijpma, A.G. Mikos, J.G.C. Wolke, and J.A. Jansen, “Injectable Calcium Phosphate Cement with PLGA, Gelatin and PTMC Microspheres in a Rabbit Femoral Defect,” Acta Biomaterialia, 7, 1752-1759 (2011).
S.A. Chew, J.D. Kretlow, P.P. Spicer, A.W. Edwards, L.S. Baggett, Y. Tabata, F.K. Kasper, and A.G. Mikos, “Delivery of Plasmid DNA Encoding Bone Morphogenetic Protein-2 with a Biodegradable Branched Polycationic Polymer in a Critical-Size Rat Cranial Defect Model,” Tissue Eng. Part A, 17, 751-763 (2011).
K. Kim, D. Dean, J. Wallace, R. Breithaupt, A.G. Mikos, and J.P. Fisher, “The Influence of Stereolithographic Scaffold Architecture and Composition on Osteogenic Signal Expression with Rat Bone Marrow Stromal Cells,” Biomaterials, 32, 3750-3763 (2011).
P.M. Mountziaris, D.C. Sing, S.A. Chew, S.N. Tzouanas, E.D. Lehman, F.K. Kasper, and A.G. Mikos, “Controlled Release of Anti-Inflammatory siRNA from Biodegradable Polymeric Microparticles Intended for Intra-Articular Delivery to the Temporomandibular Joint,” Pharm. Res., 28, 1370-1384 (2011).
M. Shi, J.D. Kretlow, P.P. Spicer, Y. Tabata, N. Demian, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Antibiotic-Releasing Porous Polymethylmethacrylate/Gelatin/Antibiotic Constructs for Craniofacial Tissue Engineering,” J. Controlled Release, 152, 196-205 (2011).
J.D. Kretlow and A.G. Mikos, “Bones to Biomaterials and Back Again – 20 Years of Taking Cues from Nature to Engineer Synthetic Polymer Scaffolds,” J. Biomed. Mater. Res. Part A, 98A, 323-331 (2011).
M. Singh, M. Pierpoint, A.G. Mikos, and F.K. Kasper, “Chondrogenic Differentiation of Neonatal Human Dermal Fibroblasts Encapsulated in Alginate Beads with Hydrostatic Compression under Hypoxic Conditions in the Presence of Bone Morphogenetic Protein-2,” J. Biomed. Mater. Res. Part A, 98A, 412-424 (2011).
J. Liao, K.E. Hammerick, G.A. Challen, M.A. Goodell, F.K. Kasper, and A.G. Mikos, “Investigating the Role of Hematopoietic Stem and Progenitor Cells in Regulating the Osteogenic Differentiation of Mesenchymal Stem Cells In Vitro,” J. Orthop. Res., 29, 1544-1553 (2011).
A.M. Henslee, P.P. Spicer, D.M. Yoon, M.B. Nair, V.V. Meretoja, K.E. Witherel, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Biodegradable Composite Scaffolds Incorporating an Intramedullary Rod and Delivering Bone Morphogenetic Protein-2 for Stabilization and Bone Regeneration in Segmental Long Bone Defects,” Acta Biomaterialia, 7, 3627-3637 (2011).
R.L. Dahlin, F.K. Kasper, and A.G. Mikos, “Polymeric Nanofibers in Tissue Engineering,” Tissue Eng. Part B: Reviews, 17, 349-364 (2011).
M.B. Nair, J.D. Kretlow, A.G. Mikos, and F.K. Kasper, “Infection and Tissue Engineering in Segmental Bone Defects – A Mini Review,” Curr. Opin. Biotechnol., 22, 721-725 (2011).
P.M. Mountziaris, P.P. Spicer, F.K. Kasper, and A.G. Mikos, “Harnessing and Modulating Inflammation in Strategies for Bone Regeneration,” Tissue Eng. Part B: Reviews, 17, 393-402 (2011).
R.A. Thibault, A.G. Mikos, and F.K. Kasper, “Protein and Mineral Composition of Osteogenic Extracellular Matrix Constructs Generated with a Flow Perfusion Bioreactor,” Biomacromolecules, 12:4204-4212 (2011).
M. Bongio, J.J.J.P. van den Beucken, M.R. Nejadnik, S.C.G. Leeuwenburgh, L.A. Kinard, F.K. Kasper, A.G. Mikos, and J.A. Jansen, “Biomimetic Modification of Synthetic Hydrogels by Incorporation of Adhesive Peptides and Calcium Phosphate Nanoparticles: In Vitro Evaluation of Cell Behavior,” Eur. Cells Mater., 22, 359-376 (2011).